Aus Pubmed

Arch Dermatol Res. 2025 Jan 18;317(1):291. doi: 10.1007/s00403-024-03786-4. ABSTRACT This study aims to explore the measurement agreement between direct and indirect health utility measures in four chronic dermatological conditions (atopic dermatitis, hidradenitis suppurativa, pemphigus, psoriasis). Outpatients survey data collected between 2015 and 2021 were analysed. Health-related quality of life (HRQoL) outcome measures included time trade-off (TTO), EQ-5D-5L and Dermatology Life Quality Ind

Arch Dermatol Res. 2025 Jan 18;317(1):282. doi: 10.1007/s00403-024-03676-9. ABSTRACT One of the most frequently impacted locations by psoriasis is the scalp. It is seen in about 80% of psoriasis cases worldwide, and its treatment is challenging. To compare the efficacy and safety of excimer light versus topical methotrexate (MTX) 1% hydrogel in treatment of scalp psoriasis. This randomized prospective intra-patient comparative study was carried out on 30 patients with scalp psoriasis. Lesions we

Arch Dermatol Res. 2025 Jan 18;317(1):286. doi: 10.1007/s00403-025-03818-7. ABSTRACT Atherosclerosis, in which chronic inflammation is also effective in it's pathogenesis, is an important cause of morbidity and mortality in psoriasis patients. Early diagnosis and management of atherosclerosis is important. Measurement of carotid intima media thickness is a method used to determine subclinical atherosclerosis. Our aim in this study is to evaluate subclinical atherosclerosis in psoriasis patients

FEBS Open Bio. 2025 Jan 17. doi: 10.1002/2211-5463.13969. Online ahead of print. ABSTRACT Dimethyl fumarate (DMF) is an anti-inflammatory and immunoregulatory medication used to treat multiple sclerosis (MS) and psoriasis. Its skin sensitization property precludes its topical use, which is unfortunate for the treatment of psoriasis. Isosorbide di-(methyl fumarate) (IDMF), a novel derivative of DMF, was synthesized to circumvent this adverse reaction and unlock the potential of topical delivery,

Prim Care Companion CNS Disord. 2025 Jan 9;27(1):24cr03803. doi: 10.4088/PCC.24cr03803. NO ABSTRACT PMID:39823455 | DOI:10.4088/PCC.24cr03803 Den ganzen Artikel lesen

JAAD Case Rep. 2024 Sep 12;53:93-96. doi: 10.1016/j.jdcr.2024.08.030. eCollection 2024 Nov. NO ABSTRACT PMID:39823053 | PMC:PMC11736064 | DOI:10.1016/j.jdcr.2024.08.030 Den ganzen Artikel lesen

JAAD Case Rep. 2024 Sep 12;53:90-92. doi: 10.1016/j.jdcr.2024.08.027. eCollection 2024 Nov. NO ABSTRACT PMID:39823051 | PMC:PMC11736156 | DOI:10.1016/j.jdcr.2024.08.027 Den ganzen Artikel lesen

Cureus. 2024 Dec 16;16(12):e75810. doi: 10.7759/cureus.75810. eCollection 2024 Dec. ABSTRACT Introduction The COVID-19 pandemic sparked an interest in skincare with the closure of spas and salons. Skincare, one of TikTok's most popular dermatology-related hashtags, received hundreds of millions of views. The American Academy of Dermatology (AAD) shared facial cleansing recommendations; however, how many people follow them is unclear. Studies have shown a good daily facial cleansing and moisturiz

Dermatol Ther (Heidelb). 2025 Jan 17. doi: 10.1007/s13555-024-01328-4. Online ahead of print. NO ABSTRACT PMID:39821856 | DOI:10.1007/s13555-024-01328-4 Den ganzen Artikel lesen

Int J Dermatol. 2025 Jan 16. doi: 10.1111/ijd.17658. Online ahead of print. NO ABSTRACT PMID:39821776 | DOI:10.1111/ijd.17658 Den ganzen Artikel lesen

Arch Dermatol Res. 2025 Jan 16;317(1):268. doi: 10.1007/s00403-025-03805-y. ABSTRACT The relationship between psoriasis and osteopenia remains undetermined. Patients with psoriasis tend to have a higher Body Mass Index (BMI) compared to those without the condition. While it appears plausible that BMI could mediate this association, further study is required to confirm this hypothesis. The objective of this study is to ascertain whether BMI plays a role in influencing the impact of psoriasis on o

Arch Dermatol Res. 2025 Jan 16;317(1):254. doi: 10.1007/s00403-025-03809-8. NO ABSTRACT PMID:39821329 | DOI:10.1007/s00403-025-03809-8 Den ganzen Artikel lesen

Arch Dermatol Res. 2025 Jan 17;317(1):269. doi: 10.1007/s00403-025-03808-9. ABSTRACT Psoriasis is associated with psychological distress among the affected due to unsightly skin lesions, chronicity and the cultural and social stigma linked with the disease. The pathophysiological link between psoriasis and depression creates a vicious cycle in the skin and brain axis. This study evaluates the psychological comorbidity of patients with chronic plaque psoriasis (CPP). A cross-sectional study was c

Arch Dermatol Res. 2025 Jan 16;317(1):256. doi: 10.1007/s00403-025-03810-1. NO ABSTRACT PMID:39820719 | DOI:10.1007/s00403-025-03810-1 Den ganzen Artikel lesen

Cell Mol Biol Lett. 2025 Jan 17;30(1):7. doi: 10.1186/s11658-025-00685-y. ABSTRACT The skin is a barrier that protects the human body against environmental factors (physical, including solar radiation, chemicals, and pathogens). The integrity and, consequently, the effective metabolic activity of skin cells is ensured by the cell membrane, the important structural and metabolic elements of which are phospholipids. Phospholipids are subject to continuous transformation, including enzymatic hydrol

Sci Rep. 2025 Jan 17;15(1):2346. doi: 10.1038/s41598-025-86976-y. ABSTRACT Brodalumab, a humanized monoclonal antibody that targets the interleukin-17 receptor A, is primarily used to manage moderate-to-severe plaque psoriasis. Although it has demonstrated favorable efficacy and safety in clinical trials, the strict inclusion and exclusion criteria may not fully reflect its safety profile in real-world settings. As its use becomes more widespread in clinical practice, understanding its safety in

Atheroscler Plus. 2024 Dec 13;59:32-38. doi: 10.1016/j.athplu.2024.12.002. eCollection 2025 Mar. ABSTRACT BACKGROUND AND AIMS: Vitamin D binding protein (DBP) serves a dual function as a vitamin D carrier and actin scavenger. Free DBP is present in high concentrations in serum, while a smaller pool is bound to lipoproteins like HDL and VLDL. The role of DBP's interaction with lipoproteins remains unclear. Given that HDL has been proposed to have both atheroprotective and anti-inflammatory proper

Bioact Mater. 2024 Dec 20;46:229-241. doi: 10.1016/j.bioactmat.2024.12.015. eCollection 2025 Apr. ABSTRACT Reactive oxygen species (ROS) at elevated levels trigger oxidative DNA damage, which is a significant factor in psoriasis exacerbation. However, normal ROS levels are essential for cell signaling, cell growth regulation, differentiation, and immune responses. To address this, we developed ROS control strategies inspired by compensatory effects. DNA nanostructures with the advantage of being

J Inflamm Res. 2025 Jan 10;18:505-517. doi: 10.2147/JIR.S493338. eCollection 2025. ABSTRACT PURPOSE: Psoriasis is a complex inflammatory skin disorder that is closely associated with metabolic syndrome (MetS). Limited information is available on skin metabolic changes in psoriasis; the effect of concurrent MetS on psoriatic skin metabolite levels is unknown. We aimed to expand this information through skin metabolomic analysis. PATIENTS AND METHODS: Untargeted metabolomics was conducted using sk

Psoriasis (Auckl). 2025 Jan 10;15:9-22. doi: 10.2147/PTT.S486338. eCollection 2025. ABSTRACT PURPOSE: Patients' treatment expectations significantly influence the effectiveness of medical and pharmacological treatments. This clinical proof-of-concept study aimed to enhance treatment outcomes by targeting positive treatment expectations of psoriasis patients beginning systemic anti-psoriatic therapy with secukinumab, an interleukin (IL)-17A antagonist. PATIENTS AND METHODS: We randomly assigned p

F1000Res. 2024 Dec 6;13:1494. doi: 10.12688/f1000research.159565.1. eCollection 2024. ABSTRACT This correspondence discusses the recent findings by Straalen et al., highlighting molecular similarities and distinctions between palmoplantar pustulosis (PPP) and dyshidrotic palmoplantar eczema (DPE). The study emphasizes shared proinflammatory pathways and T-cell-related gene upregulation while detailing unique features such as neutrophil involvement in PPP and lipid antigen processing in DPE. We e

Med J Malaysia. 2025 Jan;80(1):25-30. ABSTRACT INTRODUCTION: Psoriasis is a chronic inflammatory skin condition often associated with comorbidities that may impact cognitive function. This study aims to determine if psoriasis is associated with the risk of cognitive impairment and to assess the relationship between cognitive impairment and various disease-related factors, including psoriasis severity, disease duration, and the presence of psoriatic arthropathy, using the Virtual Cognitive Assess

J Dermatol. 2025 Jan 15. doi: 10.1111/1346-8138.17622. Online ahead of print. ABSTRACT Itch is a prominent symptom in many cutaneous disorders, including atopic dermatitis (AD), prurigo nodularis, and psoriasis. Itch is also a common but overlooked concern in patients with hidradenitis suppurativa (HS). Currently, the mechanisms underlying itch in HS remain unclear. To gain a better understanding, we reviewed the literature on pruritus in HS and other itch-predominant disorders, AD, and psoriasi

Tunis Med. 2025 Jan 5;103(1):32-43. doi: 10.62438/tunismed.v103i1.5565. ABSTRACT AIM: To develop good practice recommendations (GPR) for the therapeutic management of patients with spondyloarthritis (SpA), including psoriatic arthritis. METHODS: Following standardised procedures, a systematic review of the literature was carried out on non-pharmacological and non-biological pharmacological treatments for SpA. The review was based on questions defined by a working group of 15 rheumatologists. The

J Autoimmun. 2025 Jan 13;151:103361. doi: 10.1016/j.jaut.2025.103361. Online ahead of print. ABSTRACT Psoriasis is a chronic inflammatory skin disease with etiologies related to genetics, immunity, and the environment. It is characterized by excessive proliferation of keratinocytes and infiltration of inflammatory immune cells. Glycosylation is a post-translational modification of proteins that plays important roles in cell adhesion, signal transduction, and immune cell activation. Abnormal glyc