Ausgewählte Studien

Original Paper Background: Digital media are easily accessible without time restrictions and are widely used for health- or disease-related purposes. …Den ganzen Artikel lesen

Hautarzt. 2021 Jun 16. doi: 10.1007/s00105-021-04833-1. Online ahead of print. ABSTRACT BACKGROUND: Guidelines generally recommend an adjuvant treatment with emollients for patients suffering from psoriasis. However evidence for this purpose is limited. PATIENTS AND METHODS: We performed a prospective observational study with an emollient containing 10% urea, ceramides, glycerin and glyceryl glucoside in patients suffering from mild to moderate psoriasis. The patients had to be stable for at lea

Clin Epidemiol. 2021 May 26;13:373-382. doi: 10.2147/CLEP.S304155. eCollection 2021. ABSTRACT BACKGROUND: Most epidemiological data on vitiligo refer to selected environments or focus on the prevalence of comorbidity unrelated to the population. OBJECTIVE: Aim of the study was to gain robust representative prevalence data on vitiligo and on associated dermatologic comorbidity in the German adult population. METHODS: A dual population-based approach was applied with 1) primary data obtained betwe

Hautarzt. 2021 Jul;72(7):579-585. doi: 10.1007/s00105-021-04830-4. Epub 2021 Jun 11. ABSTRACT BACKGROUND: Our skin is a very important and complex organ of the body. The microorganisms of the skin, the so-called microbiome, represent an important part of the healthy skin barrier and are influenced by various external and internal factors. AIM: The question to what extent the skin microbiome represents a diagnostic or even therapeutic target in the context of skin diseases is discussed. MATERIALS

Introduction: Deucravacitinib, a newly approved oral medication for the treatment of patients with moderate to severe plaque psoriasis, demonstrated …Den ganzen Artikel lesen

J Dtsch Dermatol Ges. 2023 Apr 26. doi: 10.1111/ddg.15071. Online ahead of print. ABSTRACT BACKGROUND: There is a growing understanding of inflammation in psoriasis beyond its dermatological manifestation, towards systemic inflammation. Management of possible comorbidities encompassing psychological, metabolic and cardiovascular disease is recommended in national and international dermatology guidelines for treatment of psoriasis patients. Vice versa, psoriasis is being recognized as a new risk

Dermatology. 2021 Nov 25:1-10. doi: 10.1159/000520290. Online ahead of print. ABSTRACT BACKGROUND Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis that significantly impairs physical function and quality of life (QoL). Prompt therapeutic intervention is crucial for limiting PsA progression and preventing disability. OBJECTIVES The aim of this study was to compare the efficacy of brodalumab versus ustekin-umab and the im

MMW Fortschr Med. 2021 Oct;163(18):10. doi: 10.1007/s15006-021-0304-y. NO ABSTRACT PMID:34652640 | PMC:PMC8518277 | DOI:10.1007/s15006-021-0304-y Den ganzen Artikel lesen

LETTER TO THE EDITOR The cardiometabolic safety of interleukin 23 versus interleukin 17 inhibitors in psoriasis: A large-scale global cohort …Den ganzen Artikel lesen

J Dtsch Dermatol Ges. 2021 Dec;19(12):1736-1745. doi: 10.1111/ddg.14606_g. ABSTRACT Hintergrund: Die Psoriasis gilt als unabhängiger kardiovaskulärer Risikofaktor und Treiber einer Atherogenese. Mikrovaskuläre Veränderungen in psoriatischen Plaques sind gut beschrieben, wohingegen Veränderungen außerhalb betroffener Hautareale kaum untersucht wurden. In dieser Studie wurden Nagelfalzkapillaren von Psoriasispatienten in nicht betroffener Haut systematisch untersucht. Patienten und Methodik: Prosp

I-Hsin Huang, I-Hsin Huang Department of Dermatology, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan Search for more papers by this author Wei-Kai …Den ganzen Artikel lesen

Itch as the most common symptom in dermatology has been shown to be related to psychological factors such as stress, anxiety and depression. …Den ganzen Artikel lesen

LETTER TO THE EDITOR Can people take high-quality images using mobile dermatoscopes at home on easy-to-see and difficult-to-see body areas? Astrid J. …Den ganzen Artikel lesen

J Dtsch Dermatol Ges. 2021 Dec;19(12):1709-1710. doi: 10.1111/ddg.14684_g. NO ABSTRACT PMID:34894178 | DOI:10.1111/ddg.14684_g Den ganzen Artikel lesen

Original Article|Articles in Press Academic & Personal: 24 hour online access • Corporate R&D Professionals: 24 hour online access Powered ByMendeley • Add …Den ganzen Artikel lesen

Dermatol Ther. 2022 Sep 15:e15831. doi: 10.1111/dth.15831. Online ahead of print. ABSTRACT BACKGROUND: In many countries there are strong incentives for initiation of treatment with biosimilars in biologic-naïve patients and non-medical switch of ongoing treatment with originators, but real-world data regarding the outcome of these treatments are scarce. OBJECTIVES: The objective of this study is to analyze the drug survival of biosimilar adalimumab for treatment of psori

ZusammenfassungHintergrund und ZielsetzungVergleich der Wirksamkeit und Sicherheit von Biologika zur Behandlung mittelschwerer bis schwerer …Den ganzen Artikel lesen

Dermatol Ther (Heidelb). 2023 Dec 19. doi: 10.1007/s13555-023-01086-9. Online ahead of print. ABSTRACT INTRODUCTION: Given the chronic nature of psoriasis (PsO), more studies are needed that directly compare the effectiveness of different biologics over long observation periods. This study compares the effectiveness and durability through 12 months of anti-interleukin (IL)-17A biologics relative to other approved biologics in patients with moderate-to-severe psoriasis in a real-world setting. ME

J Dtsch Dermatol Ges. 2021 Oct;19(10):1451-1462. doi: 10.1111/ddg.14532_g. NO ABSTRACT PMID:34661361 | DOI:10.1111/ddg.14532_g Den ganzen Artikel lesen

J Dtsch Dermatol Ges. 2023 Nov;21(11):1351-1358. doi: 10.1111/ddg.15191_g. ABSTRACT HINTERGRUND UND ZIELSETZUNG: Die Psoriasisarthritis (PsA) erfordert für bestmögliche therapeutische Ergebnisse eine frühzeitige Diagnose und den Einsatz adäquater antirheumatischer Therapien sowie der regelmäßigen Überprüfung des Therapieerfolges. Ziel dieser Studie war es, die routinemäßigen Überwachungsmaßnahmen für Patienten mit gesicherter PsA und Psoriasis vulgaris (PsO) durch Dermatologen zu untersuchen und

Dtsch Med Wochenschr. 2024 Feb;149(3):102-105. doi: 10.1055/a-2199-1549. Epub 2024 Jan 23. ABSTRACT HISTORY AND CLINICAL FINDINGS: The 71-year-old patient reported long-standing inflammatory arthralgia due to psoriasis vulgaris. Therapy with methotrexate led to elevated liver values; the symptoms persisted under treatment with the TNFα inhibitor adalimumab. MEDICAL EXAMINATIONS: Using arthrosonography and MRI, a predominantly periarticular inflammatory pattern on the wrists, metacarpophalangea

International Journal of Rheumatic Diseases Volume 26, Issue 6 p. 1111-1119 ORIGINAL ARTICLE Restless leg syndrome in rheumatic conditions: Its …Den ganzen Artikel lesen

Commentary on ‘perceived stress in four inflammatory skin diseases: An analysis of data taken from 7273 adult subjects with acne, psoriasis, atopic …Den ganzen Artikel lesen

J Dtsch Dermatol Ges. 2024 Mar;22(3):438-441. doi: 10.1111/ddg.15305_g. NO ABSTRACT PMID:38450954 | DOI:10.1111/ddg.15305_g Den ganzen Artikel lesen

J Dtsch Dermatol Ges. 2023 May;21(5):493-503. doi: 10.1111/ddg.14994_g. ABSTRACT HINTERGRUND UND ZIELE: Die Assoziation zwischen Psoriasis und Migräne zu beurteilen. PATIENTEN UND METHODIK: MEDLINE, Embase und Cochrane Central Register of Controlled Trials wurden vom Zeitpunkt ihrer jeweiligen Gründung bis zum 1. Mai 2022 nach relevanten Beobachtungsstudien durchsucht. Die Risikoeinschätzung zur Quantifizierung der Assoziationen zwischen Psoriasis und Migräne wurde anhand einer Metaanalyse mit Z