Ausgewählte Studien

Objective: To evaluate fatigue frequency and severity among patients with psoriatic arthritis (PsA) and assess the impact of fatigue severity on …Den ganzen Artikel lesen

Objectives: To determine the individual impact of key manifestations of psoriatic arthritis (PsA) on quality of life (QoL), physical function, and …Den ganzen Artikel lesen

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Background: Psoriasis is an inflammatory disease primarily treated through molecular-targeted therapies. However, emerging evidence suggests that …Den ganzen Artikel lesen

J Invest Dermatol. 2021 Sep 23:S0022-202X(21)01409-3. doi: 10.1016/j.jid.2021.06.006. Online ahead of print. ABSTRACT Dysfunctional autophagy is linked to various diseases, including psoriasis and atopic dermatitis. Recent evidence suggests that exposure of keratinocytes to TNF-α results in impaired autophagy and lysosomal function. The skin of patients with psoriasis and atopic dermatitis reveals a decreased expression of lysosomal cathepsins. Impaired autophagy is presumably involved in inflam

Actas Dermosifiliogr. 2022 Mar 12:S0001-7310(22)00212-5. doi: 10.1016/j.ad.2022.02.028. Online ahead of print. ABSTRACT OBJECTIVE: To analyze degree of implementation of recommendations on the management of psoriasis during preconception, pregnancy, postpartum, breastfeeding, and perinatal care published by the Psoriasis Working Group of the Spanish Academy of Dermatology and Venereology (AEDV). METHODS: We designed a structured online survey consisting of closed questions. A link was emailed to

Rachel Sommer, Corresponding Author Rachel Sommer [email protected] Institute for Health Services Research in Dermatology and Nursing (IVDP), University …Den ganzen Artikel lesen

Psoriasis causes detriment in a person's physical, mental and social health which impairs their quality of life (QoL). However, the current psoriasis …Den ganzen Artikel lesen

Feist E, Baraliakos X, Behrens F, Thaçi D, Plenske A, Klaus P, Meng T. Feist E, et al. Rheumatol Ther. 2024 Feb 3. doi: 10.1007/s40744-023-00633-2. …Den ganzen Artikel lesen

Dermatol Ther (Heidelb). 2021 Oct 2. doi: 10.1007/s13555-021-00618-5. Online ahead of print. ABSTRACT INTRODUCTION: Obesity, smoking, and alcohol consumption are prevalent in psoriasis patients and have been associated with increased disease severity and reduced treatment adherence and response. This post hoc analysis of pooled data from the phase 3 AMAGINE-2 and -3 trials compared the efficacy of brodalumab versus ustekinumab in psoriasis patients with aggravating and potentiall

Tumor necrosis factor inhibitors (TNFis) are commonly used for treating psoriatic diseases; however, the risk of infection while receiving TNFis …Den ganzen Artikel lesen

Dermatologie (Heidelb). 2024 Feb 14. doi: 10.1007/s00105-023-05257-9. Online ahead of print. ABSTRACT Atopic dermatitis (AD) and psoriasis belong to the most common inflammatory dermatoses that we treat in everyday clinical practice. AD manifests in more than 70% of cases before the age of 5 years. Approximately one-third of psoriasis patients report on onset of disease in the first two decades of life. Here, we are going to review both disorders in the light of pediatric dermatology. We are goi

Dermatologie (Heidelb). 2023 Jan 2. doi: 10.1007/s00105-022-05096-0. Online ahead of print. ABSTRACT Acne, rosacea, atopic dermatitis, and psoriasis vulgaris are common inflammatory dermatoses. Of note, the epidemiology and clinical presentation of these common dermatologic diseases varies considerably between people with different colors of skin. Yet, most dermatology textbooks present and describe the clinical pictures of White people. To provide excellent dermatological care for all patients,

Hautarzt. 2021 Jun 16. doi: 10.1007/s00105-021-04833-1. Online ahead of print. ABSTRACT BACKGROUND: Guidelines generally recommend an adjuvant treatment with emollients for patients suffering from psoriasis. However evidence for this purpose is limited. PATIENTS AND METHODS: We performed a prospective observational study with an emollient containing 10% urea, ceramides, glycerin and glyceryl glucoside in patients suffering from mild to moderate psoriasis. The patients had to be stable for at lea

Harmer B, Lee S, Duong TVH, Saadabadi A. Harmer B, et al. 2024 Feb 5. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 …Den ganzen Artikel lesen

Vaccines (Basel). 2021 Aug 1;9(8):843. doi: 10.3390/vaccines9080843. ABSTRACT The risk of developing severe complications from an influenza virus infection is increased in patients with chronic inflammatory diseases such as psoriasis (PsO) and atopic dermatitis (AD). However, low influenza vaccination rates have been reported. The aim of this study was to determine vaccination rates in PsO compared to AD patients and explore patient perceptions of vaccination. A multicenter cross-sectional study

Dermatologie (Heidelb). 2023 Oct 11. doi: 10.1007/s00105-023-05234-2. Online ahead of print. ABSTRACT INTRODUCTION: A number of new, highly effective biologic drugs for psoriasis have been approved over the past few decades, which raises the question whether psoriasis is still a disease that requires inpatient treatment. METHODS: We conducted a retrospective analysis of inpatient data between 2010 and 2019 (the last 10 years prior to the coronavirus disease 2019 [COVID-19] pandemic) from three G

Br J Dermatol. 2021 Jun 2. doi: 10.1111/bjd.20527. Online ahead of print. ABSTRACT Eczema and eczematous reactions induced by interleukin (IL)-17 inhibitors in patients with psoriasis are established adverse events (1), which may be reported as adverse events (AEs) in up to 12.1% patients on anti-IL-17 treatment in controlled clinical trials (2-5). We performed an integrated safety analysis of 13 clinical studies to evaluate the frequency and management of the treatment-emergent adverse events (

Interactive effect of genetic and environmental risk factors on Psoriasis: current evidence and future directivesDen ganzen Artikel lesen

Importance: Generalized pustular psoriasis (GPP) lacks internationally accepted definitions and diagnostic criteria, impeding timely diagnosis and …Den ganzen Artikel lesen

JAMA Dermatol. 2022 Mar 30. doi: 10.1001/jamadermatol.2022.0434. Online ahead of print. ABSTRACT IMPORTANCE: A clear dosing regimen for methotrexate in psoriasis is lacking, and this might lead to a suboptimal treatment. Because methotrexate is affordable and globally available, a uniform dosing regimen could potentially optimize the treatment of patients with psoriasis worldwide. OBJECTIVE: To reach international consensus among psoriasis experts on a uniform dosing regimen for treatment with m

Elwenspoek MM, Thom H, Sheppard AL, Keeney E, O'Donnell R, Jackson J, Roadevin C, Dawson S, Lane D, Stubbs J, Everitt H, Watson JC, Hay AD, Gillett …Den ganzen Artikel lesen

Research letter| Volume 88, ISSUE 5, P1129-1131, May 2023 Academic & Personal: 24 hour online access • Corporate R&D Professionals: 24 hour online …Den ganzen Artikel lesen

• Cameron A.C. • Miller D.L. A practitioner’s guide to cluster-robust inference. Journal of human resources. 2015; 50: 317-372 Farzanfar D. • Dowlati Y. • French …Den ganzen Artikel lesen

Eur J Dermatol. 2021 Aug 26. doi: 10.1684/ejd.2021.4087. Online ahead of print. NO ABSTRACT PMID:34463279 | DOI:10.1684/ejd.2021.4087 Den ganzen Artikel lesen