Ausgewählte Studien

Original Paper Background: Psoriasis (PsO) is a chronic, systemic, immune-mediated disease with multiorgan involvement. Psoriatic arthritis (PsA) is …Den ganzen Artikel lesen

Key words To the Editor: Patients with and dermatologists treating psoriasis usually strive for complete skin clearance, yet some patients prefer …Den ganzen Artikel lesen

Ann Rheum Dis. 2023 Mar 27:annrheumdis-2022-222852. doi: 10.1136/ard-2022-222852. Online ahead of print. ABSTRACT The 'MHC-I (major histocompatibility complex class I)-opathy' concept describes a family of inflammatory conditions with overlapping clinical manifestations and a strong genetic link to the MHC-I antigen presentation pathway. Classical MHC-I-opathies such as spondyloarthritis, Behçet's disease, psoriasis and birdshot uveitis are widely recognised for their strong asso

Acta Derm Venereol. 2023 Mar 28;103:adv5087. doi: 10.2340/actadv.v103.5087. ABSTRACT Patients with psoriasis have a higher prevalence of cardiovascular risk factors. This study evaluated cardiovascular screening practices and statin prescribing habits among dermatologists, rheumatologists and primary care physicians (PCPs) through an online questionnaire, which was distributed through the Spanish scientific societies of the above-mentioned specialties. A total of 299 physicians (103 dermatologis

Drugs. 2023 Mar 28. doi: 10.1007/s40265-023-01857-w. Online ahead of print. ABSTRACT Axial symptoms (i.e., back pain) are common in the general population. At the same time 25-70% of patients with psoriatic arthritis (PsA) exhibit signs of inflammatory axial involvement (axial PsA). The presence of unexplained chronic (duration ≥ 3 months) back pain in a patient with psoriasis or PsA should trigger evaluation of the presence of axial involvement. Evaluation of axial involvement normally involves

Dermatologie (Heidelb). 2023 Mar 28:1-8. doi: 10.1007/s00105-023-05132-7. Online ahead of print. ABSTRACT Psoriasis is nowadays regarded as a multifactorial, inflammatory, immune-mediated systemic condition with predominant involvement of the skin. It starts in about one third of cases in childhood and adolescence and is often accompanied by marked impairment of the quality of life of sufferers and their parents. Aside from genetic disposition, trigger factors such as streptococcal infections ar

Den ganzen Artikel lesen

Psoriasis vulgaris is a systemic, chronic inflammatory disease affecting 2–3% of the population. Recent advances in the understanding of the pathophyDen ganzen Artikel lesen

Dattola A, Silvestri M, Bennardo L, Del Duca E, Longo C, Bianchi L, Nisticò S. Dattola A, et al. Dermatol Ther. 2018 Nov;31(6):e12728. doi: …Den ganzen Artikel lesen

Dermatologie (Heidelb). 2023 Mar 21:1-4. doi: 10.1007/s00105-023-05140-7. Online ahead of print. ABSTRACT Generalized pustular psoriasis (GPP) is often a life-threatening disease which, in contrast to psoriasis vulgaris, is associated with the formation of sterile pustules on the skin. Until recently, there was no approved treatment in Europe, so that drugs used for psoriasis vulgaris were also frequently used for GPP. However, new studies showed that, in GPP, mutation of the interleukin-36 rece

There is a lack of evidence investigating the impact of patient-reported outcomes (PROs) monitoring in routine clinical practice, according to a …Den ganzen Artikel lesen

Full text linksCite Display options Display options Objective: To evaluate the randomized controlled trials (RCTs) of Curcumin and Curcuma longa Extract …Den ganzen Artikel lesen

Background Psoriatic arthritis (PsA) is a chronic, immune-mediated inflammatory disease with heterogenous musculoskeletal manifestation (arthritis, …Den ganzen Artikel lesen

RMD Open. 2023 Mar;9(1):e002936. doi: 10.1136/rmdopen-2022-002936. ABSTRACT OBJECTIVE: To investigate the influence of COVID-19 vaccination on disease activity in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients under targeted therapies. PATIENTS AND METHODS: 1765 vaccinated patients COVID-19, 1178 (66.7%) with RA and 587 (33.3%) with PsA from the COVID-19 registry in patients with rheumatic diseases (COVIDSER) project, were included. Demographics, disease characteristics, Diseas

LETTER TO THE EDITOR A Cross-sectional Comparison of Eczema and Psoriasis Patients with Regards to Cardiovascular Disease and Risk Factors N. …Den ganzen Artikel lesen

Augustin M, Spehr C, Radtke MA, Boehncke WH, Luger T, Mrowietz U, Reusch M, Strömer K, Wozel G, von Kiedrowski R, Rustenbach SJ, Purwins S, Reich K. …Den ganzen Artikel lesen

Autoimmun Rev. 2023 Mar 15;22(5):103312. doi: 10.1016/j.autrev.2023.103312. Online ahead of print. ABSTRACT More than 10 disease-modifying therapies (DMT) are approved by the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA) for the treatment of multiple sclerosis (MS) and new therapeutic options are on the horizon. Due to different underlying therapeutic mechanisms, a more individualized selection of DMTs in MS is possible, taking into account the patient's current s

J Eur Acad Dermatol Venereol. 2023 Mar 13. doi: 10.1111/jdv.19039. Online ahead of print. NO ABSTRACT PMID:36914370 | DOI:10.1111/jdv.19039 Den ganzen Artikel lesen

Actas Dermosifiliogr. 2023 Mar 9:S0001-7310(23)00172-2. doi: 10.1016/j.ad.2023.02.016. Online ahead of print. ABSTRACT The advent of biosimilar drugs and their use in routine clinical practice has revolutionized the management of moderate to severe psoriasis and led to changes in the positioning of the existing molecules used to control this condition. Evidence from clinical trials complemented by real-world experience has helped to clarify concepts and has significantly changed the use and posi

RMD Open. 2023 Mar;9(1):e002837. doi: 10.1136/rmdopen-2022-002837. ABSTRACT BACKGROUND: Psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA) show certain overlaps: A subset of patients with PsA can develop axial involvement (axial PsA, axPsA), while a subset of patients with axSpA presents with psoriasis (axSpA+pso). Treatment strategy for axPsA is mostly based on axSpA evidence. OBJECTIVES: To compare demographic and disease-specific parameters of axPsA and axSpA+pso. METHODS: RABBIT-S

Dermatologie (Heidelb). 2023 Apr;74(4):232-242. doi: 10.1007/s00105-023-05122-9. Epub 2023 Mar 10. ABSTRACT The dermoscope was initially used in dermatology to distinguish between pigmented and nonpigmented tumors, both benign and malignant. Over the last two decades, however, the spectrum of dermoscopy has broadened and its role in the diagnosis of nonneoplastic diseases, in particular inflammatory skin diseases, has become increasingly important. In the diagnosis of general and inflammatory sk

RMD Open. 2023 Mar;9(1):e002960. doi: 10.1136/rmdopen-2022-002960. ABSTRACT OBJECTIVE: To assess polypharmacy in women and men with psoriatic arthritis (PsA). METHODS: From the German BARMER health insurance database, 11 984 persons with PsA and disease-modifying antirheumatic drug therapy in 2021 were included and compared with sex-matched and age-matched controls without inflammatory arthritis. Medications were analysed by Anatomical Therapeutic Chemical (ATC) groups. Polypharmacy (≥5 concomit

J Invest Dermatol. 2023 Mar 6:S0022-202X(23)00156-2. doi: 10.1016/j.jid.2023.02.015. Online ahead of print. ABSTRACT Highly effective targeted therapies are available to treat non-communicable chronic inflammatory skin diseases (ncISD). In contrast, the exact diagnosis of ncISD is complicated by their complex pathogenesis and clinical and histological overlap. Particularly, differential diagnosis of psoriasis and eczema can be challenging in special cases and molecular diagnostic tools need to b

Highly effective targeted therapies are available to treat non-communicable chronic inflammatory skin diseases (ncISD). In contrast, the exact …Den ganzen Artikel lesen

Full text linksCite Display options Display options Background: To date, no large study has examined the relationship between psoriasis and dementia in …Den ganzen Artikel lesen