Ausgewählte Studien

SummaryBackground and objectivesPsoriasis is a common skin disorder with a high physical and psychological burden for patients. Up to 30% of the …Den ganzen Artikel lesen

1. Griffiths CEM, Armstrong AW, Gudjonsson JE, Barker J. Psoriasis. Lancet. 2021;397(10281):1301–1315. doi: 10.1016/s0140-6736(20)32549-6 [PubMed] …Den ganzen Artikel lesen

Mao KL, Fan ZL, Yuan JD, Chen PP, Yang JJ, Xu J, ZhuGe DL, Jin BH, Zhu QY, Shen BX, Sohawon Y, Zhao YZ, Xu HL. Mao KL, et al. Colloids Surf B …Den ganzen Artikel lesen

Actas Dermosifiliogr. 2024 Feb 19:S0001-7310(24)00154-6. doi: 10.1016/j.ad.2024.02.013. Online ahead of print. ABSTRACT Several studies suggest that patients with psoriasis have a higher incidence of neoplasms or recurrence, especially of the skin, which could be associated with the use of therapies to treat psoriasis. Furthermore, the evidence available on the safety profile of some treatments in this context, and the management of these patients is scarce, which is why clinical practice guidel

Hautarzt. 2021 Nov 25. doi: 10.1007/s00105-021-04913-2. Online ahead of print. ABSTRACT BACKGROUND: Psoriasis (Pso) and atopic dermatitis (AD) are chronic skin diseases that result in significant physical and psychological impairment, financial burden, and loss of quality of life. According to previous data, there are regional differences in healthcare. OBJECTIVES: The aim was to analyse the epidemiology as well as the treatment of insured people with Pso and AD in Germany in a regional comparis

Dermatologie (Heidelb). 2023 Mar 21:1-4. doi: 10.1007/s00105-023-05140-7. Online ahead of print. ABSTRACT Generalized pustular psoriasis (GPP) is often a life-threatening disease which, in contrast to psoriasis vulgaris, is associated with the formation of sterile pustules on the skin. Until recently, there was no approved treatment in Europe, so that drugs used for psoriasis vulgaris were also frequently used for GPP. However, new studies showed that, in GPP, mutation of the interleukin-36 rece

LETTER TO THE EDITOR Corresponding Author Marie Aleth Richard CEReSS-EA 3279, Research Centrer in Health Services and Quality of Life Aix Marseille …Den ganzen Artikel lesen

Editor’s summary Inflammatory skin diseases such as psoriasis are typically treated with immunosuppressants, but side effects and cost limit their …Den ganzen Artikel lesen

Actas Dermosifiliogr. 2023 Oct 25:S0001-7310(23)00847-5. doi: 10.1016/j.ad.2023.10.016. Online ahead of print. ABSTRACT BACKGROUND AND OBJECTIVE: Although the Spanish Ministry of Health prepares national therapeutic positioning reports (TPRs) and drug reimbursement policies, each of the country's 17 autonomous communities is responsible for health care services and prescription requirements in its territory. The aim of the EQUIDAD study was to describe and explore potential differences in prescr

SummaryThe incidence of autoimmune diseases in industrialized countries is constantly increasing over past decades. These diseases lead to increased …Den ganzen Artikel lesen

logistic J Dermatolog Treat. 2022 Aug 18:1-12. doi: 10.1080/09546634.2022.2115285. Online ahead of print. ABSTRACT OBJECTIVES: Fumaric acid esters (FAEs) are a well-established treatment option for long-term therapy of moderate to severe plaque psoriasis. This study examines effectiveness of FAEs for the treatment of plaque psoriasis in real-world practice at 12 months and if patient characteristics affect the odds of clinical response. METHODS: A descriptive, mul

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International Journal of Rheumatic Diseases Volume 26, Issue 6 p. 1111-1119 ORIGINAL ARTICLE Restless leg syndrome in rheumatic conditions: Its …Den ganzen Artikel lesen

BackgroundPsoriasis is a chronic inflammatory condition with cutaneous and systemic involvement. Although many efficacious treatment options are …Den ganzen Artikel lesen

Inn Med (Heidelb). 2023 Jan;64(1):102-106. doi: 10.1007/s00108-022-01414-9. Epub 2022 Dec 14. NO ABSTRACT PMID:36515721 | DOI:10.1007/s00108-022-01414-9 Den ganzen Artikel lesen

Background: The risk of developing cutaneous T cell lymphoma (CTCL) in patients using psoriasis biologics has not been well characterized. The goals …Den ganzen Artikel lesen

J Crohns Colitis. 2021 Dec 3:jjab213. doi: 10.1093/ecco-jcc/jjab213. Online ahead of print. ABSTRACT BACKGROUND: Immunomediated adverse events (IAEs) are the most frequently reported infliximab-related adverse events. Combination therapy may reduce their incidence, although this strategy is not recommended in elderly patients. AIMS: To compare the rates of infliximab-related IAE and loss of response (LOR) in elderly and younger patients. METHODS: Adult patients in the ENEIDA registry who had rec

Table 1. Characteristics of the included studies. Study Design Study Drug Drug Dose No. of Participants Total Patient Years of Exposure Age, Mean (SD) Male, …Den ganzen Artikel lesen

RMD Open. 2021 Dec;7(3):e001975. doi: 10.1136/rmdopen-2021-001975. ABSTRACT OBJECTIVES: This study aims to provide a comprehensive analysis of the age-dependent risk of psoriatic arthritis (PsA). For this purpose, it focuses on the varying incidences within the different age groups. METHODS: The data were collected as part of the morbidity-based risk adjustment of the statutory health insurance companies in Germany. This survey recorded the International Statistical Classification of Diseases an

Biomed Pharmacother. 2024 Feb;171:116127. doi: 10.1016/j.biopha.2024.116127. Epub 2024 Jan 9. ABSTRACT The lipid content of skin plays a determinant role in its barrier function with a particularly important role attributed to linoleic acid and its derivatives. Here we explored the consequences of interfering with the soluble epoxide hydrolase (sEH) on skin homeostasis. sEH; which converts fatty acid epoxides generated by cytochrome P450 enzymes to their corresponding diols, was largely restrict

Dattola A, Silvestri M, Bennardo L, Del Duca E, Longo C, Bianchi L, Nisticò S. Dattola A, et al. Dermatol Ther. 2018 Nov;31(6):e12728. doi: …Den ganzen Artikel lesen

Br J Dermatol. 2023 Oct 17:ljad382. doi: 10.1093/bjd/ljad382. Online ahead of print. ABSTRACT BACKGROUND: Safety is an important consideration in decisions on treatment for patients with moderate to severe psoriasis and its study is the main purpose of the BIOBADADERM Registry. The combination of a biologic agent and a conventional systemic drug- generally methotrexate (MTX)-is a common treatment in clinical practice. However, there is a paucity of evidence from real-world practice on the safety

Full text linksCite Display options Display options Background: Selenium sulfide, available as a shampoo or topical lotion at 1%, or 2.5% concentrations …Den ganzen Artikel lesen

Augustin M, Spehr C, Radtke MA, Boehncke WH, Luger T, Mrowietz U, Reusch M, Strömer K, Wozel G, von Kiedrowski R, Rustenbach SJ, Purwins S, Reich K. …Den ganzen Artikel lesen

J Eur Acad Dermatol Venereol. 2023 Mar 13. doi: 10.1111/jdv.19039. Online ahead of print. NO ABSTRACT PMID:36914370 | DOI:10.1111/jdv.19039 Den ganzen Artikel lesen