Ausgewählte Studien

Skornicki M, Prince P, Suruki R, Lee E, Louder A. Skornicki M, et al. Adv Ther. 2021 May;38(5):2458-2471. doi: 10.1007/s12325-021-01698-7. Epub 2021 …Den ganzen Artikel lesen

Feist E, Baraliakos X, Behrens F, Thaçi D, Plenske A, Klaus P, Meng T. Feist E, et al. Rheumatol Ther. 2024 Feb 3. doi: 10.1007/s40744-023-00633-2. …Den ganzen Artikel lesen

• McInnes IB, Mease PJ, Kirkham B, et al. Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE …Den ganzen Artikel lesen

Actas Dermosifiliogr. 2024 Mar 5:S0001-7310(24)00187-X. doi: 10.1016/j.ad.2024.02.030. Online ahead of print. ABSTRACT BACKGROUND AND OBJECTIVE: risankizumab-a humanized monoclonal antibody that targets the p19 subunit of IL-23-has been recently approved to treat moderate-to-severe plaque psoriasis. Real-world data based on a representative pool of patients are currently lacking. OBJECTIVE: To assess the mid- and long-term safety and efficacy profile of risankizumab in patients with moderate-to-

Dermatologie (Heidelb). 2024 Mar 7. doi: 10.1007/s00105-024-05310-1. Online ahead of print. ABSTRACT Psoriasis is a chronic inflammatory systemic disease that requires optimal long-term management due to its high prevalence in the population and the numerous comorbidities that severely impair quality of life. A variety of treatment options are now available. In addition to objective skin findings and a specific location such as nails or genital area, the presence of psoriatic arthritis and other

J Dtsch Dermatol Ges. 2024 Mar;22(3):438-441. doi: 10.1111/ddg.15305_g. NO ABSTRACT PMID:38450954 | DOI:10.1111/ddg.15305_g Den ganzen Artikel lesen

Dermatol Ther (Heidelb). 2024 Mar 5. doi: 10.1007/s13555-024-01109-z. Online ahead of print. ABSTRACT INTRODUCTION: Limited information exists on the epidemiology, treatment, and burden of palmoplantar pustulosis (PPP) and defining the optimal course of treatment remains challenging without approved targeted treatments in most countries. Here, we describe the clinical and demographic characteristics, treatments received, and negative health outcomes experienced among patients with PPP in the Uni

Front Immunol. 2024 Feb 16;15:1334844. doi: 10.3389/fimmu.2024.1334844. eCollection 2024. ABSTRACT Sebaceous glands drive acne, however, their role in other inflammatory skin diseases remains unclear. To shed light on their potential contribution to disease development, we investigated the spatial transcriptome of sebaceous glands in psoriasis and atopic dermatitis patients across lesional and non-lesional human skin samples. Both atopic dermatitis and psoriasis sebaceous glands expressed genes

ZusammenfassungHintergrund und ZieleDie Assoziation zwischen Psoriasis und Migräne zu beurteilen.Patienten und MethodikMEDLINE, Embase und Cochrane …Den ganzen Artikel lesen

Dear Editor, Psoriasis is associated with a number of comorbidities of which some can be positively influenced by lifestyle changes.1-3 It is also …Den ganzen Artikel lesen

Journal of the European Academy of Dermatology and Venereology Volume 38, Issue 3 p. 460-461 Free Access Jacek C. Szepietowski, Corresponding Author Jacek …Den ganzen Artikel lesen

J Autoimmun. 2024 Feb 22;144:103183. doi: 10.1016/j.jaut.2024.103183. Online ahead of print. ABSTRACT Chronic nonbacterial osteomyelitis (CNO), an autoinflammatory bone disease primarily affecting children, can cause pain, hyperostosis and fractures, affecting quality-of-life and psychomotor development. This study investigated CNO-associated variants in P2RX7, encoding for the ATP-dependent trans-membrane K+ channel P2X7, and their effects on NLRP3 inflammasome assembly. Whole exome sequencing

LETTER TO THE EDITOR Corresponding Author Marie Aleth Richard CEReSS-EA 3279, Research Centrer in Health Services and Quality of Life Aix Marseille …Den ganzen Artikel lesen

1. Jungen D, Augustin M, Langenbruch A, Zander N, Reich K, Strömer K, et al.. Cost-of-illness of psoriasis – results of a German cross-sectional …Den ganzen Artikel lesen

Actas Dermosifiliogr. 2024 Feb 19:S0001-7310(24)00150-9. doi: 10.1016/j.ad.2024.02.009. Online ahead of print. ABSTRACT BACKGROUND: Psoriasis is a chronic inflammatory dermatosis whose clinical and topographic distribution requires differential diagnosis, or the possible association with allergic contact dermatitis (ACD), requiring patch testing (PT) as part of the diagnostic procedure. OBJECTIVES: To describe the epidemiological, clinical, and allergic profile of patients with a primary or seco

Actas Dermosifiliogr. 2024 Feb 19:S0001-7310(24)00154-6. doi: 10.1016/j.ad.2024.02.013. Online ahead of print. ABSTRACT Several studies suggest that patients with psoriasis have a higher incidence of neoplasms or recurrence, especially of the skin, which could be associated with the use of therapies to treat psoriasis. Furthermore, the evidence available on the safety profile of some treatments in this context, and the management of these patients is scarce, which is why clinical practice guidel

Ixekizumab im Vergleich zu Fumarsäureestern und Methotrexat bei der Behandlung der Nagelpsoriasis bei Patienten mit mittelschwerer bis schwerer …Den ganzen Artikel lesen

Dermatologie (Heidelb). 2024 Feb 14. doi: 10.1007/s00105-023-05257-9. Online ahead of print. ABSTRACT Atopic dermatitis (AD) and psoriasis belong to the most common inflammatory dermatoses that we treat in everyday clinical practice. AD manifests in more than 70% of cases before the age of 5 years. Approximately one-third of psoriasis patients report on onset of disease in the first two decades of life. Here, we are going to review both disorders in the light of pediatric dermatology. We are goi

Adv Ther. 2024 Feb 7. doi: 10.1007/s12325-023-02779-5. Online ahead of print. ABSTRACT INTRODUCTION: Immune-mediated inflammatory diseases (IMID) are a group of disorders characterized by chronic inflammation caused by an altered immune regulation in targeted organs or systems. IMID itself could have an implied increased risk of venous thromboembolism (VTE) and this risk varies throughout the course of the disease as well as with some contraceptive methods and treatments. The aim of this study w

Actas Dermosifiliogr. 2024 Feb 5:S0001-7310(24)00082-6. doi: 10.1016/j.ad.2023.07.028. Online ahead of print. ABSTRACT BACKGROUND: The past 5 years have seen a proliferation of new treatments for atopic dermatitis (AD). We analyzed recent drug survival data for cyclosporine in this setting. Because the Spanish National Healthcare system requires patients with AD to be treated with cyclosporine before they can be prescribed other systemic treatments, drug survival for cyclosporine may be shorter

Acta Derm Venereol. 2024 Feb 7;104:adv12430. doi: 10.2340/actadv.v104.12430. ABSTRACT There are regional differences in the prevalence of psoriasis between countries, as well as within countries. However, regional determinants of differences in prevalence are not yet understood. The aim of this study was to identify sociodemographic and environmental determinants of regional prevalence rates for psoriasis. Analyses were based on German outpatient billing data from statutory health insurance, tog

Objective: This study aimed to investigate the prevalence of depressive symptoms in patients with psoriasis and the association between depressive …Den ganzen Artikel lesen

Background: Psoriasis is a genetically determined systemic skin disease, although environmental trigger factors are required for disease …Den ganzen Artikel lesen

G. Biazus Soares, G. Biazus Soares Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, Miami Itch Center, University of Miami Miller …Den ganzen Artikel lesen

Dear Editor, Sleep is a physiological process that accounts for almost one third of a person's life.1 Sleep disturbances (SDs) are distressing and …Den ganzen Artikel lesen